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January 2025

· 3 min read

This release note includes:

  • Updates to the eProtein Discovery Software (5.0.0)
  • Updates to the eProtein Discovery Screen Experiment (5.2.2)
  • Updates to the eProtein Discovery Cloud Software
  • Bug fixes and improvements

New workflow release: eProtein Discovery™ Screen Experiment 5.2.2 workflow​

warning

This workflow will only be available on instruments that has been updated to software version 5.0.0. The following features will not be available retrospectively.

  • Fix for cartridge pins not retracting when retrying a cartridge connection failure
  • Fix for cartridge pins not retracting when starting a new experiment after a previous experiment was aborted or failed
  • Droplet movements have been updated to ensure it stays away from the edge of the cartridge. This enhancement will improve droplet flow and prevent reagent backflow

eProtein Discovery™ Instrument software release 5.0.0​

User interface updates:

  • Instrument software updates are now automatically performed when the instrument is powered on, connected to the network, and idle. By default the updates occur at 1 am, but this time can be changed in the settings menu.
  • The instrument time zone can now be adjusted on the settings screen
  • Run scripts are added to each video that detail the actual events occurring during the workflow
  • Instrument shutdown function is disabled if run report generation is in progress
  • The "Open/Close Drawer" and "Connect/Disconnect Cartridge" options in the side menu are now disabled during experiments to prevent accidental cartridge detachment during a run

Bug fixes:

  • The operating system has been updated to address a memory leak issue that could lead to system shutdowns.
  • Fix for missing 3C Protease scissors icons and legend in PDF report
  • Fix for occasional hang during PDF generation
  • Fix for temperature control being left on after an experiment ends
  • A correction has been implemented to resolve access issues for new users who were unable to log in to the instrument.

eProtein Discovery (cloud) software release​

  • eProtein Discovery Cloud software will be locked for 15 minutes after 10 successive unsuccessful sign-in attempts in a 24 hour period. This feature is designed to protect users from unauthorized access and enhance account security
  • A link to the Nuclera Knowledge base is now accessible through the Help menu
  • The experiment design page now supports the addition of up to 16 custom additives. Users can select ADD01-ADD16 in the additive selection panel and are encouraged to list the identify of each additives in the Notes section